Successful cryopreservation of human ovarian cortex tissues using supercooling

Successful cryopreservation of human ovarian cortex tissues using supercooling

The development of new method to cryopreserve human ovarian cortex tissues without damage is needed for the improvement of quality of life (QOL) of female cancer patients. Here we show novel cryopreservation method of human ovarian cortex tissues by using supercooling (S.C.) procedure. Our method will be helpful in order to preserve fertility of female cancer patients.

ADDENDUM: Successful cryopreservation of human ovarian cortex tissues using supercooling

Editorial Note: Successful cryopreservation of human ovarian cortex tissues using supercooling Scientific Reports has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this paper. The situation is being investigated.

Malignant cells are not found in ovarian cortex from breast cancer patients undergoing ovarian cortex cryopreservation.

BACKGROUND Breast cancer is a frequent indication for ovarian cortex cryopreservation due to its high incidence. The main concern of this procedure is the possibility of reintroducing metastatic cells within the implant, an issue that has not been addressed systematically. Thus, a study was designed to analyse the presence of ovarian metastases in breast cancer patients undergoing ovarian tissu...

Human Ovarian Tissue Cryopreservation as Fertility Reserve

Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium

Osteoarthritis (OA) is a degenerative joint disease affecting cartilage and is the most common form of arthritis worldwide. One third of OA patients have severe synovitis and less than 10% have no evidence of synovitis. Moreover, synovitis is predictive for more severe disease progression. This offers a target for therapy but more research on the pathophysiological processes in the synovial tis...